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Limited information is available on the acute toxicity of fexofenadine in humans; however, dizziness, drowsiness, and dry mouth have been reported. Single fexofenadine hydrochloride doses up to 800 mg and fexofenadine hydrochloride dosages of 690 mg twice daily for 1 month or fexofenadine hydrochloride dosages of 240 mg once daily for 1 year have been well tolerated in adults.
For the treatment of fexofenadine overdosage, usual measures to remove unabsorbed drug from the GI tract, and supportive and symptomatic treatment should be initiated. Experience with terfenadine, the parent drug, indicates that fexofenadine is not effectively removed by hemodialysis.
